OPINION: Dr Ken Romeo 775-870-6942
Genomic instability and genetic alterations are characteristics shared by cancer, aging and other disease states.
Sirtuins (SIRTs) are substances that regulate gene expression in cellular metabolic status.
SIRTs can modulate chromatin function through direct deacetylation of histones and by promoting altered methylation of histones and DNA, leading to repression of gene alteration. This concept is critical.
SIRTs also interact with a broad range of regulators and target gene expression both positively and negatively.
SIRT inhibition may be beneficial in decreasing the risk of some cancers, while SIRT activation can exert positive anti aging effects and help prevent age-related disease and cancers.
Thus, SIRT modulation may positively affect the treatment of cancer and age-related disorders.
The study indicated below reviewed the emerging data regarding SIRTs in cancer and aging. The study found SIRTs to be an important regulator of genomic stability.
We are providing this data ahead of publication in DNA Cell Biology.
The Ten Most Common Sirtuin (SIRTs) Food: (Source: Wikipedia)*
- Green Tea.
- Dark chocolate (that is at least 85 per cent cocoa)
- Citrus fruits.
- Red Wine.*
Source: DNA Cell Biol. 2016 Jul 5 (Ahead of publication)
Yours in Health!
Dr. Ken Romeo
Dr. Ken Romeo is a Principal and Chief Clinical Data Coordinator for the Healthy Aging Research Foundation (HARF) in Reno, NV.
Though each article contained on this Blog is derived from published Clinical and Research data contained in various national and international databases with links provided,
NO ARTICLE OR CONCLUSION IS MEANT TO DIAGNOSE, TREAT, PREVENT OR CURE DISEASE.
CONSULT YOUR HEALTH PROFESSIONAL BEFORE MAKING ANY CHANGES TO YOUR HEALTH REGIMEN.
* The HARF does not recommend the regular consumption of alcoholic beverages.