OPINION: Dr Ken Romeo 775-870-6942
A clinical study was recently conducted to determine whether oral supplementation with a fermented papaya preparation (FPP-treated group) or an antioxidant cocktail (antioxidant-control group, composed of 10 mg trans-resveratrol, 60 µg selenium, 10 mg vitamin E and 50 mg vitamin C) was able to improve the skin antioxidant capacity and the expression of key skin genes, while promoting skin anti aging effects.
The study enrolled 60 healthy non-smoker males and females aged 40-65 years, all of whom showed clinical signs of skin aging. The subjects were randomly divided into two
matched groups, and were administered FPP or the antioxidant treatment of a 4.5 g/day sachet sublingually twice a day for 90 days in a double-blind fashion.
The parameters investigated were: Skin surface, brown spots, skin evenness, skin moisturization, elasticity (face), redox balance, nitric oxide (NO) concentration, and the expression levels of key genes (outer forearm sample).
As compared with the baseline (day 0) and antioxidant-control values, FPP-treated subjects showed a significant improvement in skin evenness, moisturization and elasticity.
This finding suggests that orally-administered FPP showed a consistent biological and gene-regulatory improvement in the skin, as has also demonstrated in previous experimental and clinical trials testing other tissues, while common oral antioxidants had only a minor effect.
Yours in Health!
Dr. Ken Romeo
Dr. Ken Romeo is a Principal and Chief Clinical Data Coordinator for the Healthy Aging Research and Genomic Council (HARGC) in Reno, NV.
Though each article contained on this Blog is derived from published Clinical and Research data contained in various national and international databases with links provided,
NO ARTICLE OR CONCLUSION IS MEANT TO DIAGNOSE, TREAT, PREVENT OR CURE DISEASE.
CONSULT YOUR HEALTH PROFESSIONAL BEFORE MAKING ANY CHANGES TO YOUR HEALTH REGIMEN.
Source: Exp Ther Med. 2016 Mar;11(3):909-916. Epub 2016 Jan 20.